Cargando…
Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe
BACKGROUND: Drug potency is a pharmacological parameter defining dose or concentration of drug required to obtain 50% of the drug’s maximal effect. Pharmacokinetic-pharmacodynamic modelling and simulation allows estimation of potency and evaluate strategies improving treatment outcome. The objective...
Autores principales: | Ngara, Bernard, Zvada, Simbarashe, Chawana, Tariro Dianah, Nhachi, Charles Fungai Brian, Rusakaniko, Simbarashe |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147021/ https://www.ncbi.nlm.nih.gov/pubmed/34030726 http://dx.doi.org/10.1186/s40360-021-00497-8 |
Ejemplares similares
-
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents
por: Ngara, Bernard, et al.
Publicado: (2020) -
Evaluating an enhanced adherence intervention among HIV positive adolescents failing atazanavir/ritonavir-based second line antiretroviral treatment at a public health clinic
por: Chawana, Tariro Dianah, et al.
Publicado: (2017) -
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe
por: Dhoro, Milcah, et al.
Publicado: (2015) -
Prevalence and associated factors of smoking among secondary school students in Harare Zimbabwe
por: Bandason, Tsitsi, et al.
Publicado: (2010) -
A Characterisation and Profiling of District Health Indicators in Zimbabwe: An Application of Principal Component Analysis in a Data Limited Setting
por: Shamu, Shepherd, et al.
Publicado: (2015)