Metformin Dysregulates the Unfolded Protein Response and the WNT/β-Catenin Pathway in Endometrial Cancer Cells through an AMPK-Independent Mechanism

Multiple lines of evidence suggest that metformin, an antidiabetic drug, exerts anti-tumorigenic effects in different types of cancer. Metformin has been reported to affect cancer cells’ metabolism and proliferation mainly through the activation of AMP-activated protein kinase (AMPK). Here, we show...

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Detalles Bibliográficos
Autores principales: Conza, Domenico, Mirra, Paola, Calì, Gaetano, Insabato, Luigi, Fiory, Francesca, Beguinot, Francesco, Ulianich, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147131/
https://www.ncbi.nlm.nih.gov/pubmed/33946426
http://dx.doi.org/10.3390/cells10051067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147131/
https://www.ncbi.nlm.nih.gov/pubmed/33946426
http://dx.doi.org/10.3390/cells10051067

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