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Metformin Dysregulates the Unfolded Protein Response and the WNT/β-Catenin Pathway in Endometrial Cancer Cells through an AMPK-Independent Mechanism

Multiple lines of evidence suggest that metformin, an antidiabetic drug, exerts anti-tumorigenic effects in different types of cancer. Metformin has been reported to affect cancer cells’ metabolism and proliferation mainly through the activation of AMP-activated protein kinase (AMPK). Here, we show...

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Detalles Bibliográficos
Autores principales:	Conza, Domenico, Mirra, Paola, Calì, Gaetano, Insabato, Luigi, Fiory, Francesca, Beguinot, Francesco, Ulianich, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147131/ https://www.ncbi.nlm.nih.gov/pubmed/33946426 http://dx.doi.org/10.3390/cells10051067

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