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Vaccination with Prion Peptide-Displaying Polyomavirus-Like Particles Prolongs Incubation Time in Scrapie-Infected Mice

Prion diseases like scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt–Jakob disease (CJD) in humans are fatal neurodegenerative diseases characterized by the conformational conversion of the normal, mainly α-helical cellular prion protein (PrP(C)) into the abnormal β-...

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Detalles Bibliográficos
Autores principales: Eiden, Martin, Gedvilaite, Alma, Leidel, Fabienne, Ulrich, Rainer G., Groschup, Martin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147134/
https://www.ncbi.nlm.nih.gov/pubmed/33946367
http://dx.doi.org/10.3390/v13050811