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Isolation and Proteomics of the Insulin Secretory Granule

Insulin, a vital hormone for glucose homeostasis is produced by pancreatic beta-cells and when secreted, stimulates the uptake and storage of glucose from the blood. In the pancreas, insulin is stored in vesicles termed insulin secretory granules (ISGs). In Type 2 diabetes (T2D), defects in insulin...

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Detalles Bibliográficos
Autores principales: Norris, Nicholas, Yau, Belinda, Kebede, Melkam Alamerew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147143/
https://www.ncbi.nlm.nih.gov/pubmed/33946444
http://dx.doi.org/10.3390/metabo11050288