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Targeting Bacterial Sortases in Search of Anti-virulence Therapies with Low Risk of Resistance Development
Increasingly ineffective antibiotics and rapid spread of multi- and pan-resistant bacteria represent a global health threat; hence, the need of developing new antimicrobial medicines. A first step in this direction is identifying new molecular targets, such as virulence factors. Sortase A represents...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147154/ https://www.ncbi.nlm.nih.gov/pubmed/33946434 http://dx.doi.org/10.3390/ph14050415 |