The SOS Error-Prone DNA Polymerase V Mutasome and β-Sliding Clamp Acting in Concert on Undamaged DNA and during Translesion Synthesis

In the mid 1970s, Miroslav Radman and Evelyn Witkin proposed that Escherichia coli must encode a specialized error-prone DNA polymerase (pol) to account for the 100-fold increase in mutations accompanying induction of the SOS regulon. By the late 1980s, genetic studies showed that SOS mutagenesis re...

Descripción completa

Detalles Bibliográficos
Autores principales: Sikand, Adhirath, Jaszczur, Malgorzata, Bloom, Linda B., Woodgate, Roger, Cox, Michael M., Goodman, Myron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147279/
https://www.ncbi.nlm.nih.gov/pubmed/34062858
http://dx.doi.org/10.3390/cells10051083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147279/
https://www.ncbi.nlm.nih.gov/pubmed/34062858
http://dx.doi.org/10.3390/cells10051083

Ejemplares similares