Mutation-Based Antibiotic Resistance Mechanism in Methicillin-Resistant Staphylococcus aureus Clinical Isolates

β-Lactam antibiotics target penicillin-binding proteins and inhibit the synthesis of peptidoglycan, a crucial step in cell wall biosynthesis. Staphylococcus aureus acquires resistance against β-lactam antibiotics by producing a penicillin-binding protein 2a (PBP2a), encoded by the mecA gene. PBP2a p...

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Detalles Bibliográficos
Autores principales: Ali, Tanveer, Basit, Abdul, Karim, Asad Mustafa, Lee, Jung-Hun, Jeon, Jeong-Ho, Rehman, Shafiq ur, Lee, Sang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147353/
https://www.ncbi.nlm.nih.gov/pubmed/34062812
http://dx.doi.org/10.3390/ph14050420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147353/
https://www.ncbi.nlm.nih.gov/pubmed/34062812
http://dx.doi.org/10.3390/ph14050420

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