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The TSPO Ligands MGV-1 and 2-Cl-MGV-1 Differentially Inhibit the Cigarette Smoke-Induced Cytotoxicity to H1299 Lung Cancer Cells

SIMPLE SUMMARY: In this study, we investigated the impact of CS on various TSPO-related mitochondrial processes, and the protective ability of our novel TSPO ligands against such CS-induced cellular damages. Our results support the previously reported role of TSPO in apoptotic cell death. Moreover,...

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Detalles Bibliográficos
Autores principales: Zeineh, Nidal, Nagler, Rafael M., Gabay, Martin, Obeid, Fadi, Kahana, Meygal, Weizman, Abraham, Gavish, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147464/
https://www.ncbi.nlm.nih.gov/pubmed/34063262
http://dx.doi.org/10.3390/biology10050395