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Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression

Glioblastoma (GBM) is the most common and malignant primary brain tumor. Glioblastoma stem cells (GSCs) not only initiate and sustain uncontrolled cell proliferation but also resistant to conventional clinical therapies including temozolomide (TMZ) dependent chemotherapy and radiotherapy, implying t...

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Detalles Bibliográficos
Autores principales: Liu, Kun, Pu, Jun, Nie, Zhi, Shi, Yulin, Jiang, Liping, Wu, Qisheng, Chen, Yongbin, Yang, Cuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147559/
https://www.ncbi.nlm.nih.gov/pubmed/34046412
http://dx.doi.org/10.3389/fcell.2021.678209