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Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs Its Signaling Pathways in Liver and Adipose Tissue in Mice

Spinal cord injury (SCI) results in dysregulation of carbohydrate and lipid metabolism; the underlying cellular and physiological mechanisms remain unclear. Fibroblast growth factor 21 (FGF21) is a circulating protein primarily secreted by the liver that lowers blood glucose levels, corrects abnorma...

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Detalles Bibliográficos
Autores principales: Liu, Xin-Hua, Graham, Zachary A., Harlow, Lauren, Pan, Jiangping, Azulai, Daniella, Bauman, William A., Yarrow, Joshua, Cardozo, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147560/
https://www.ncbi.nlm.nih.gov/pubmed/34046014
http://dx.doi.org/10.3389/fendo.2021.668984