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Gab2 (Grb2-Associated Binder2) Plays a Crucial Role in Inflammatory Signaling and Endothelial Dysfunction

In response to inflammatory insult, endothelial cells express cell adhesion molecules and TF (tissue factor), leading to increased adhesion of leukocytes to the endothelium and activation of coagulation. Enhanced coagulation could further exacerbate inflammation. Identifying key signaling molecule(s...

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Detalles Bibliográficos
Autores principales: Kondreddy, Vijay, Magisetty, Jhansi, Keshava, Shiva, Rao, L. Vijaya Mohan, Pendurthi, Usha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147699/
https://www.ncbi.nlm.nih.gov/pubmed/33827252
http://dx.doi.org/10.1161/ATVBAHA.121.316153