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EEG and Sleep Effects of Tramadol Suggest Potential Antidepressant Effects with Different Mechanisms of Action

Tramadol is a widely used, centrally acting, opioid analgesic compound, with additional inhibitory effects on the synaptic reuptake of serotonin and noradrenaline, as well as on the 5-HT(2) and NMDA receptors. Preclinical and clinical evidence also suggests its therapeutic potential in the treatment...

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Detalles Bibliográficos
Autores principales: Koncz, Szabolcs, Papp, Noémi, Menczelesz, Noémi, Pothorszki, Dóra, Bagdy, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147808/
https://www.ncbi.nlm.nih.gov/pubmed/34064349
http://dx.doi.org/10.3390/ph14050431