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Regio- and diastereoselective dearomatizations of N-alkyl activated azaarenes: the maximization of the reactive sites

An unprecedented base-promoted multi-component one-pot dearomatization of N-alkyl activated azaarenes was developed, which enabled the synthesis of complex and diverse bridged cyclic polycycles with multiple stereocenters in a highly regio- and diastereoselective manner. Besides, we realized the ste...

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Detalles Bibliográficos
Autores principales: Miao, Hong-Jie, Wang, Le-Le, Han, Hua-Bin, Zhao, Yong-De, Wang, Qi-Lin, Bu, Zhan-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147894/
https://www.ncbi.nlm.nih.gov/pubmed/34123266
http://dx.doi.org/10.1039/c9sc04880d