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Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase

During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity of α-N-acetylgalactosaminidase (α-NaGalase) from hu...

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Detalles Bibliográficos
Autores principales: Utkina, Natalia, Likhatskaya, Galina, Malyarenko, Olesya, Ermakova, Svetlana, Balabanova, Larisa, Slepchenko, Lubov, Bakunina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147984/
https://www.ncbi.nlm.nih.gov/pubmed/34063022
http://dx.doi.org/10.3390/biomedicines9050510