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Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase
During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity of α-N-acetylgalactosaminidase (α-NaGalase) from hu...
Autores principales: | Utkina, Natalia, Likhatskaya, Galina, Malyarenko, Olesya, Ermakova, Svetlana, Balabanova, Larisa, Slepchenko, Lubov, Bakunina, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147984/ https://www.ncbi.nlm.nih.gov/pubmed/34063022 http://dx.doi.org/10.3390/biomedicines9050510 |
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