Automated Sequential Analysis of Hydrophilic and Lipophilic Fractions of Biological Samples: Increasing Single-Injection Chemical Coverage in Untargeted Metabolomics

In order to increase metabolite coverage in LC–MS-based untargeted metabolomics, HILIC- and RPLC-mode separations are often combined. Unfortunately, these two techniques pose opposite requirements on sample composition, necessitating either dual sample preparations, increasing needed sample volume,...

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Detalles Bibliográficos
Autores principales: Pirttilä, Kristian, Laurell, Göran, Pettersson, Curt, Hedeland, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147996/
https://www.ncbi.nlm.nih.gov/pubmed/34063084
http://dx.doi.org/10.3390/metabo11050295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147996/
https://www.ncbi.nlm.nih.gov/pubmed/34063084
http://dx.doi.org/10.3390/metabo11050295

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