Mutual Effects of Hydrogen Bonding and Polymer Hydrophobicity on Ibuprofen Crystal Inhibition in Solid Dispersions with Poly(N-vinyl pyrrolidone) and Poly(2-oxazolines)

Poly(N-vinyl pyrrolidone) (PVP), poly(2-methyl-2-oxazoline) (PMOZ), poly(2-ethyl-2-oxazoline) (PEOZ), poly(2-n-propyl-2-oxazoline) (PnPOZ), and poly(2-isopropyl-2-oxazoline) (PiPOZ) were used to prepare solid dispersions with ibuprofen (IB), a model poorly-water soluble drug. Dispersions, prepared b...

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Detalles Bibliográficos
Autores principales: Shan, Xiaoning, Moghul, Maryam A., Williams, Adrian C., Khutoryanskiy, Vitaliy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148000/
https://www.ncbi.nlm.nih.gov/pubmed/34064530
http://dx.doi.org/10.3390/pharmaceutics13050659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148000/
https://www.ncbi.nlm.nih.gov/pubmed/34064530
http://dx.doi.org/10.3390/pharmaceutics13050659

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