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Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice

Metabolic syndrome is a clustering of metabolic disorder with unclear molecular mechanism. Increasing studies have found that the pathogenesis and progression of metabolic syndrome are closely related to inflammation. Here, we report celastrol, a traditional Chinese medicine, can improve high fat di...

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Detalles Bibliográficos
Autores principales: Zhu, Yuyu, Wan, Ning, Shan, Xinni, Deng, Guoliang, Xu, Qiang, Ye, Hui, Sun, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148064/
https://www.ncbi.nlm.nih.gov/pubmed/34094828
http://dx.doi.org/10.1016/j.apsb.2020.12.008