Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson's disease treatment

The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown to have neuroprotective effects on experimental Parkinson's disease (PD) models. FLZ is under phase Ⅰ clinical trial now, while...

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Detalles Bibliográficos
Autores principales: Shang, Junmei, Ma, Shurong, Zang, Caixia, Bao, Xiuqi, Wang, Yan, Zhang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148066/
https://www.ncbi.nlm.nih.gov/pubmed/34094829
http://dx.doi.org/10.1016/j.apsb.2021.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148066/
https://www.ncbi.nlm.nih.gov/pubmed/34094829
http://dx.doi.org/10.1016/j.apsb.2021.01.009

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