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Gut microbiota mediates the absorption of FLZ, a new drug for Parkinson's disease treatment

The gut microbiota plays an important role in regulating the pharmacokinetics and pharmacodynamics of many drugs. FLZ, a novel squamosamide derivative, has been shown to have neuroprotective effects on experimental Parkinson's disease (PD) models. FLZ is under phase Ⅰ clinical trial now, while...

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Detalles Bibliográficos
Autores principales:	Shang, Junmei, Ma, Shurong, Zang, Caixia, Bao, Xiuqi, Wang, Yan, Zhang, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148066/ https://www.ncbi.nlm.nih.gov/pubmed/34094829 http://dx.doi.org/10.1016/j.apsb.2021.01.009

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