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Escape from abluminal LRP1-mediated clearance for boosted nanoparticle brain delivery and brain metastasis treatment

Breast cancer brain metastases (BCBMs) are one of the most difficult malignancies to treat due to the intracranial location and multifocal growth. Chemotherapy and molecular targeted therapy are extremely ineffective for BCBMs due to the inept brain accumulation because of the formidable blood‒brain...

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Detalles Bibliográficos
Autores principales: Khan, Naveed Ullah, Ni, Jiang, Ju, Xiufeng, Miao, Tongtong, Chen, Haiyan, Han, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148067/
https://www.ncbi.nlm.nih.gov/pubmed/34094838
http://dx.doi.org/10.1016/j.apsb.2020.10.015