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In Vitro Synergistic Inhibition of HT-29 Proliferation and 2H-11 and HUVEC Tubulogenesis by Bacopaside I and II Is Associated with Ca(2+) Flux and Loss of Plasma Membrane Integrity

We previously showed how triterpene saponin bacopaside (bac) II, purified from the medicinal herb Bacopa monnieri, induced cell death in colorectal cancer cell lines and reduced endothelial cell migration and tube formation, and further demonstrated a synergistic effect of a combination of bac I and...

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Detalles Bibliográficos
Autores principales: Tomita, Yoko, Smith, Eric, Palethorpe, Helen M., Nakhjavani, Maryam, Yeo, Kenny K. L., Townsend, Amanda R., Price, Timothy J., Yool, Andrea J., Hardingham, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148107/
https://www.ncbi.nlm.nih.gov/pubmed/34066415
http://dx.doi.org/10.3390/ph14050436