Calcium and Redox Liaison: A Key Role of Selenoprotein N in Skeletal Muscle

Selenoprotein N (SEPN1) is a type II glycoprotein of the endoplasmic reticulum (ER) that senses calcium levels to tune the activity of the sarcoplasmic reticulum calcium pump (SERCA pump) through a redox-mediated mechanism, modulating ER calcium homeostasis. In SEPN1-depleted muscles, altered ER cal...

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Detalles Bibliográficos
Autores principales: Zito, Ester, Ferreiro, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148124/
https://www.ncbi.nlm.nih.gov/pubmed/34066362
http://dx.doi.org/10.3390/cells10051116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148124/
https://www.ncbi.nlm.nih.gov/pubmed/34066362
http://dx.doi.org/10.3390/cells10051116

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