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Calcium and Redox Liaison: A Key Role of Selenoprotein N in Skeletal Muscle
Selenoprotein N (SEPN1) is a type II glycoprotein of the endoplasmic reticulum (ER) that senses calcium levels to tune the activity of the sarcoplasmic reticulum calcium pump (SERCA pump) through a redox-mediated mechanism, modulating ER calcium homeostasis. In SEPN1-depleted muscles, altered ER cal...
Autores principales: | Zito, Ester, Ferreiro, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148124/ https://www.ncbi.nlm.nih.gov/pubmed/34066362 http://dx.doi.org/10.3390/cells10051116 |
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