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Role of Surfactant Micellization for Enhanced Dissolution of Poorly Water-Soluble Cilostazol Using Poloxamer 407-Based Solid Dispersion via the Anti-Solvent Method

This study aimed to investigate the role of micellization of sodium lauryl sulfate (SLS) in poloxamer 407 (POX)-based solid dispersions (POX-based SDs) using the anti-solvent method in enhancing the dissolution rate of practically water-insoluble cilostazol (CLT). Herein, SLS was incorporated into C...

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Detalles Bibliográficos
Autores principales: Jin, Gang, Ngo, Hai V., Cui, Jing-Hao, Wang, Jie, Park, Chulhun, Lee, Beom-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148127/
https://www.ncbi.nlm.nih.gov/pubmed/34063136
http://dx.doi.org/10.3390/pharmaceutics13050662