PEDF-Mediated Mitophagy Triggers the Visual Cycle by Enhancing Mitochondrial Functions in a H(2)O(2)-Injured Rat Model

Retinal degenerative diseases result from oxidative stress and mitochondrial dysfunction, leading to the loss of visual acuity. Damaged retinal pigment epithelial (RPE) and photoreceptor cells undergo mitophagy. Pigment epithelium-derived factor (PEDF) protects from oxidative stress in RPE and impro...

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Detalles Bibliográficos
Autores principales: Kim, Jae Yeon, Park, Sohae, Park, Hee Jung, Kim, Se Ho, Lew, Helen, Kim, Gi Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148157/
https://www.ncbi.nlm.nih.gov/pubmed/34066394
http://dx.doi.org/10.3390/cells10051117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148157/
https://www.ncbi.nlm.nih.gov/pubmed/34066394
http://dx.doi.org/10.3390/cells10051117

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