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Metabolic inhibitors of bacterial glycan biosynthesis

The bacterial cell wall is a quintessential drug target due to its critical role in colonization of the host, pathogen survival, and immune evasion. The dense cell wall glycocalyx contains distinctive monosaccharides that are absent from human cells, and proper assembly of monosaccharides into highe...

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Detalles Bibliográficos
Autores principales: Williams, Daniel A., Pradhan, Kabita, Paul, Ankita, Olin, Ilana R., Tuck, Owen T., Moulton, Karen D., Kulkarni, Suvarn S., Dube, Danielle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148367/
https://www.ncbi.nlm.nih.gov/pubmed/34123271
http://dx.doi.org/10.1039/c9sc05955e