Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition

The mitochondrial ATP synthase emerges as key hub of cellular functions controlling the production of ATP, cellular signaling, and fate. It is regulated by the ATPase inhibitory factor 1 (IF1), which is highly abundant in neurons. Herein, we ablated or overexpressed IF1 in mouse neurons to show that...

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Detalles Bibliográficos
Autores principales: Esparza-Moltó, Pau B., Romero-Carramiñana, Inés, Núñez de Arenas, Cristina, Pereira, Marta P., Blanco, Noelia, Pardo, Beatriz, Bates, Georgina R., Sánchez-Castillo, Carla, Artuch, Rafael, Murphy, Michael P., Esteban, José A., Cuezva, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148373/
https://www.ncbi.nlm.nih.gov/pubmed/33983919
http://dx.doi.org/10.1371/journal.pbio.3001252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148373/
https://www.ncbi.nlm.nih.gov/pubmed/33983919
http://dx.doi.org/10.1371/journal.pbio.3001252

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