Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy

There is an alarming scarcity of novel chemical matter with bioactivity against multidrug-resistant Gram-negative bacterial pathogens. Cystobactamids, recently discovered natural products from myxobacteria, are an exception to this trend. Their unusual chemical structure, composed of oligomeric para...

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Detalles Bibliográficos
Autores principales: Testolin, Giambattista, Cirnski, Katarina, Rox, Katharina, Prochnow, Hans, Fetz, Verena, Grandclaudon, Charlotte, Mollner, Tim, Baiyoumy, Alain, Ritter, Antje, Leitner, Christian, Krull, Jana, van den Heuvel, Joop, Vassort, Aurelie, Sordello, Sylvie, Hamed, Mostafa M., Elgaher, Walid A. M., Herrmann, Jennifer, Hartmann, Rolf W., Müller, Rolf, Brönstrup, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148378/
https://www.ncbi.nlm.nih.gov/pubmed/34123255
http://dx.doi.org/10.1039/c9sc04769g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148378/
https://www.ncbi.nlm.nih.gov/pubmed/34123255
http://dx.doi.org/10.1039/c9sc04769g

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