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Silencing long noncoding RNA NEAT1 alleviates acute liver failure via the EZH2-mediated microRNA-139/PUMA axis

This study aimed to investigate the role of long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) in the development of ALF. We collected blood samples from patients with acute liver failure (ALF) and established an ALF mouse model induced by D-galactosamine/Lipopolysaccharide (...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Liu, Shu, Wang, Huan, Liu, Lian, Zhang, Sheng, Ming, Yingzi, Zhao, Yujun, Cheng, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148447/
https://www.ncbi.nlm.nih.gov/pubmed/33901015
http://dx.doi.org/10.18632/aging.202927