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RO4929097 regulates RANKL-induced osteoclast formation and LPS-mediated bone resorption

To investigate the suppressive function of RO4929097, a potent -secretase inhibitor, on RANKL-induced osteoclastogenesis. The cytotoxicity of RO4929097 was evaluated. The suppressive effect and possible molecular mechanism of RO4929097 on RANKL-induced osteoclastogenesis was evaluated both in vitro...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Zhao, Congyun, Zhao, Yi, Zhou, Yuan, Wang, Lei, Hang, Donghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148457/
https://www.ncbi.nlm.nih.gov/pubmed/33934091
http://dx.doi.org/10.18632/aging.202926