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Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1

UV radiation is one of the main contributors to skin photoaging by promoting the accumulation of cellular senescence, which in turn induces a proinflammatory and tissue-degrading state that favors skin aging. The members of the sirtuin family of NAD(+)-dependent enzymes play an anti-senescence role...

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Detalles Bibliográficos
Autores principales: Martínez-Gutiérrez, Alfredo, Fernández-Duran, Irene, Marazuela-Duque, Anna, Simonet, Nicolás G., Yousef, Ibraheem, Martínez-Rovira, Immaculada, Martínez-Hoyos, Josefina, Vaquero, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148468/
https://www.ncbi.nlm.nih.gov/pubmed/33901008
http://dx.doi.org/10.18632/aging.203010