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Shikimic acid protects skin cells from UV-induced senescence through activation of the NAD+-dependent deacetylase SIRT1
UV radiation is one of the main contributors to skin photoaging by promoting the accumulation of cellular senescence, which in turn induces a proinflammatory and tissue-degrading state that favors skin aging. The members of the sirtuin family of NAD(+)-dependent enzymes play an anti-senescence role...
Autores principales: | Martínez-Gutiérrez, Alfredo, Fernández-Duran, Irene, Marazuela-Duque, Anna, Simonet, Nicolás G., Yousef, Ibraheem, Martínez-Rovira, Immaculada, Martínez-Hoyos, Josefina, Vaquero, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148468/ https://www.ncbi.nlm.nih.gov/pubmed/33901008 http://dx.doi.org/10.18632/aging.203010 |
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