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Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

Age-related macular degeneration (AMD) is a worldwide leading cause of blindness affecting individuals over 50 years old. The most aggressive form, wet AMD, is characterized by choroidal neovascularization (CNV) and inflammation involving microglia recruitment. By using a laser-induced CNV mouse mod...

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Detalles Bibliográficos
Autores principales: Roblain, Quentin, Louis, Thomas, Yip, Cassandre, Baudin, Louis, Struman, Ingrid, Caolo, Vincenza, Lambert, Vincent, Lecomte, Julie, Noël, Agnès, Heymans, Stephane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148470/
https://www.ncbi.nlm.nih.gov/pubmed/33952723
http://dx.doi.org/10.18632/aging.203035