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Supplementary research on K150del variant of activated protein C

Activated protein C (APC) is an anticoagulant with potent cytoprotective and anti-inflammatory effects. K150del, a natural variant of APC, is associated with reduced anticoagulant activity. We performed a comprehensive study to analyze the functional alterations of the K150del mutant. Transcriptome...

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Detalles Bibliográficos
Autores principales: Lin, Wen-Yi, Tang, Liang, Lu, Xuan, Hu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148483/
https://www.ncbi.nlm.nih.gov/pubmed/33896796
http://dx.doi.org/10.18632/aging.202904