Internal modulation of proteolysis in vascular extracellular matrix remodeling: role of ADAM metallopeptidase with thrombospondin type 1 motif 5 in the development of intracranial aneurysm rupture

Intracranial aneurysms (IAs) are common cerebrovascular diseases that carry a high mortality rate, and the mechanisms that contribute to IA formation and rupture have not been elucidated. ADAMTS-5 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif 5) is a secreted proteinase involved in matrix...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Weihan, Zhang, Hao, Hou, Changkai, Liu, Quanlei, Yang, Shuyuan, Zhang, Zhen, Yang, Weidong, Yang, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148490/
https://www.ncbi.nlm.nih.gov/pubmed/33934089
http://dx.doi.org/10.18632/aging.202948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148490/
https://www.ncbi.nlm.nih.gov/pubmed/33934089
http://dx.doi.org/10.18632/aging.202948

Ejemplares similares