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Capsanthin induces G1/S phase arrest, erlotinib-sensitivity and inhibits tumor progression by suppressing EZH2-mediated epigenetically silencing of p21 in triple-negative breast cancer cells

Capsanthin is a naturally occurring red pepper carotenoid with possible antitumor activity, but its antitumor mechanisms have yet to be delineated. We tested the anti-proliferative activity of capsanthin with human triple-negative breast cancer (TNBC) and found that cell proliferation was inhibited...

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Detalles Bibliográficos
Autores principales: Wu, Jia-Yan, Chien, Yi-Chung, Tsai, I-Chen, Hung, Chih-Chiang, Huang, Wei-Chien, Liu, Liang-Chih, Yu, Yung-Luen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148495/
https://www.ncbi.nlm.nih.gov/pubmed/33934088
http://dx.doi.org/10.18632/aging.202925