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Capsanthin induces G1/S phase arrest, erlotinib-sensitivity and inhibits tumor progression by suppressing EZH2-mediated epigenetically silencing of p21 in triple-negative breast cancer cells
Capsanthin is a naturally occurring red pepper carotenoid with possible antitumor activity, but its antitumor mechanisms have yet to be delineated. We tested the anti-proliferative activity of capsanthin with human triple-negative breast cancer (TNBC) and found that cell proliferation was inhibited...
Autores principales: | Wu, Jia-Yan, Chien, Yi-Chung, Tsai, I-Chen, Hung, Chih-Chiang, Huang, Wei-Chien, Liu, Liang-Chih, Yu, Yung-Luen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148495/ https://www.ncbi.nlm.nih.gov/pubmed/33934088 http://dx.doi.org/10.18632/aging.202925 |
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