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SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes

Brown adipose tissue (BAT) activity plays a key role in regulating systemic energy. The activation of BAT results in increased energy expenditure, making this tissue an attractive pharmacological target for therapies against obesity and type 2 diabetes. Sirtuin 5 (SIRT5) affects BAT function by regu...

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Detalles Bibliográficos
Autores principales: Molinari, Francesca, Feraco, Alessandra, Mirabilii, Simone, Saladini, Serena, Sansone, Luigi, Vernucci, Enza, Tomaselli, Giada, Marzolla, Vincenzo, Rotili, Dante, Russo, Matteo A., Ricciardi, Maria Rosaria, Tafuri, Agostino, Mai, Antonello, Caprio, Massimiliano, Tafani, Marco, Armani, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148511/
https://www.ncbi.nlm.nih.gov/pubmed/34066961
http://dx.doi.org/10.3390/cells10051126