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Structural Studies on an Anti-Angiogenic Peptide Using Molecular Modeling

BACKGROUND: Development of VEGF antagonists, which inhibit its interaction with the receptors, is a widely used strategy for the inhibition of angiogenesis and tumor growth. OBJECTIVES: In the present study, a VEGFR-1 antagonistic peptide was designed and its potential for binding to VEGFR-1 and VEG...

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Detalles Bibliográficos
Autores principales: Assareh, Elham, Mehrnejad, Faramarz, Asghari, S. Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148638/
https://www.ncbi.nlm.nih.gov/pubmed/34056022
http://dx.doi.org/10.30498/IJB.2020.2553