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Effects of Linker Flexibility and Conformational Changes of IP3 Receptor on Split Luciferase Complementation Assay

BACKGROUND: IP3-induced Ca2+ release, mediated by IP3R, is one of the most momentous cellular signaling mechanisms that regulate in a wide variety of essential cellular functions. Involvement of disrupted IP3 signaling pathways in numerous pathophysiology conditions is implicated to find the best me...

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Detalles Bibliográficos
Autores principales: Moradi, Maryam, Hosseinkhani, Saman, Arab, Seyed Shahriar, Khammari, Anahita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148647/
https://www.ncbi.nlm.nih.gov/pubmed/34056016
http://dx.doi.org/10.30498/IJB.2020.2423