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Robust single-cell discovery of RNA targets of RNA binding proteins and ribosomes

RNA binding proteins (RBPs) are critical regulators of gene expression and RNA processing that are required for gene function. Yet, the dynamics of RBP regulation in single cells is unknown. To address this gap in understanding, we developed STAMP (Surveying Targets by APOBEC Mediated Profiling), wh...

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Detalles Bibliográficos
Autores principales: Brannan, Kristopher W., Chaim, Isaac A., Marina, Ryan J., Yee, Brian A., Kofman, Eric R., Lorenz, Daniel A., Jagannatha, Pratibha, Dong, Kevin D., Madrigal, Assael A., Underwood, Jason G., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148648/
https://www.ncbi.nlm.nih.gov/pubmed/33963355
http://dx.doi.org/10.1038/s41592-021-01128-0