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Similarities and differences in the conformational stability and reversibility of ORF8, an accessory protein of SARS-CoV-2, and its L84S variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has the characteristic accessory protein ORF8. Although clinical reports indicate that ORF8 variant strains (Δ382 and L84S variants) are less likely to cause severe illness, functional dif...

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Detalles Bibliográficos
Autores principales: Ohki, Shinya, Imamura, Tomohiro, Higashimura, Yasuki, Matsumoto, Kenji, Mori, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149210/
https://www.ncbi.nlm.nih.gov/pubmed/34062392
http://dx.doi.org/10.1016/j.bbrc.2021.05.074