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Epidermal Growth Factor Protects Against High Glucose-Induced Podocyte Injury Possibly via Modulation of Autophagy and PI3K/AKT/mTOR Signaling Pathway Through DNA Methylation

AIM: Diabetic nephropathy (DN) is a serious health problem worldwide. Epidermal growth factor (EGF) has suggested as a potential biomarker for the progression of chronic kidney disease. In this study, we examined the effects of EGF on the high glucose (HG)-induced podocyte injury and explored the un...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Deng, Ming, Ke, Xiao, Lei, Xiangyang, Ju, Hao, Liu, Zhiming, Bai, Xiaosu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149214/
https://www.ncbi.nlm.nih.gov/pubmed/34045875
http://dx.doi.org/10.2147/DMSO.S299562