Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells

Dry age-related macular degeneration (AMD) is characterised by loss of central vision and currently has no approved medical treatment. Dysregulation of the complement system is thought to play an important role in disease pathology and supplementation of Complement Factor I (CFI), a key regulator of...

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Detalles Bibliográficos
Autores principales: Dreismann, Anna K., McClements, Michelle E., Barnard, Alun R., Orhan, Elise, Hughes, Jane P., Lachmann, Peter J., MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149295/
https://www.ncbi.nlm.nih.gov/pubmed/33750925
http://dx.doi.org/10.1038/s41434-021-00239-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149295/
https://www.ncbi.nlm.nih.gov/pubmed/33750925
http://dx.doi.org/10.1038/s41434-021-00239-9

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