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Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells
Dry age-related macular degeneration (AMD) is characterised by loss of central vision and currently has no approved medical treatment. Dysregulation of the complement system is thought to play an important role in disease pathology and supplementation of Complement Factor I (CFI), a key regulator of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149295/ https://www.ncbi.nlm.nih.gov/pubmed/33750925 http://dx.doi.org/10.1038/s41434-021-00239-9 |