Efficacy, safety and tolerability of drugs studied in phase 3 randomized controlled trials in solid tumors over the last decade

Data suggest that for newly approved cancer drugs safety and tolerability are worse than in control arms of registration trials. Less is known about the balance between efficacy and toxicity of drugs studied in unselected phase 3 randomized controlled trials (RCTs) including those not resulting in r...

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Detalles Bibliográficos
Autores principales: Ribnikar, Domen, Goldvaser, Hadar, Veitch, Zachary W., Ocana, Alberto, Templeton, Arnoud J., Šeruga, Boštjan, Amir, Eitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149406/
https://www.ncbi.nlm.nih.gov/pubmed/34035370
http://dx.doi.org/10.1038/s41598-021-90403-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149406/
https://www.ncbi.nlm.nih.gov/pubmed/34035370
http://dx.doi.org/10.1038/s41598-021-90403-3

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