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What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?

Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.

Detalles Bibliográficos
Autor principal: Holst, Jens Juul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149460/
https://www.ncbi.nlm.nih.gov/pubmed/34095885
http://dx.doi.org/10.1016/j.xcrm.2021.100284