Cargando…
What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?
Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates.
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149460/ https://www.ncbi.nlm.nih.gov/pubmed/34095885 http://dx.doi.org/10.1016/j.xcrm.2021.100284 |
| _version_ | 1783697966671855616 |
|---|---|
| author | Holst, Jens Juul |
| author_facet | Holst, Jens Juul |
| author_sort | Holst, Jens Juul |
| collection | PubMed |
| description | Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates. |
| format | Online Article Text |
| id | pubmed-8149460 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-81494602021-06-03 What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? Holst, Jens Juul Cell Rep Med Preview Lu et al.(1) previously demonstrated that antagonist antibodies against the GIP receptor promote weight loss combined with GLP-1. They now elegantly developed a conjugate of GIPR antibodies and GLP-1 and show effective weight loss in obese non-human primates. Elsevier 2021-05-18 /pmc/articles/PMC8149460/ /pubmed/34095885 http://dx.doi.org/10.1016/j.xcrm.2021.100284 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Preview Holst, Jens Juul What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title | What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_full | What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_fullStr | What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_full_unstemmed | What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_short | What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists? |
| title_sort | what combines best with glp-1 for obesity treatment: gip receptor agonists or antagonists? |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8149460/ https://www.ncbi.nlm.nih.gov/pubmed/34095885 http://dx.doi.org/10.1016/j.xcrm.2021.100284 |
| work_keys_str_mv | AT holstjensjuul whatcombinesbestwithglp1forobesitytreatmentgipreceptoragonistsorantagonists |